Is bacterial DNA a better marker than endotoxin of bacterial translocation in decompensated cirrhosis?
نویسندگان
چکیده
منابع مشابه
Bacterial translocation markers in liver cirrhosis
Bacterial translocation (BT) is an important mechanism in the development of infection in liver cirrhosis. The migration and colonization of bacteria and/or bacterial products from the bowel to mesenteric lymph nodes is a controlled process in healthy persons. Increased intestinal permeability, bacterial overgrowth and defect of gut-associated lymphatic tissue promote impaired BT in cirrhotics....
متن کاملIs there any change in the pattern of bacterial translocation with increased time of the obstruction?
Introduction: Bacterial translocation is defined as the passage of bacteria from intestinal tract to the extraintestinal organs such as the peritoneum and blood circulation. The aim of this study is to examine bacterial translocation (regarding type of bacteria and effect of time of obstruction on bacterial translocation) from intestinal lumen to the peritoneum and viscera in acute, simple mec...
متن کاملBacterial DNA induces a proinflammatory immune response in patients with decompensated cirrhosis
We read with interest the study of Thalheimer et al (Gut 2005;54:556–63) in which they reviewed actual knowledge regarding the influence of infection on haemodynamics, variceal haemorrhage, heparinoid effects, liver damage, and other effects. We agree with these assumptions and would like to add information not quoted in the paper that may help explain some of the immune abnormalities usually f...
متن کاملBacterial DNA induces a proinflammatory immune response in patients with decompensated cirrhosis.
We read with interest the study of Thalheimer et al (Gut 2005;54:556–63) in which they reviewed actual knowledge regarding the influence of infection on haemodynamics, variceal haemorrhage, heparinoid effects, liver damage, and other effects. We agree with these assumptions and would like to add information not quoted in the paper that may help explain some of the immune abnormalities usually f...
متن کاملDetection of bacterial DNA by in situ hybridization in patients with decompensated liver cirrhosis
BACKGROUND Spontaneous bacterial peritonitis (SBP) is often difficult to diagnose because bacteria in ascites cannot be detected accurately by conventional culture. In situ hybridization (ISH) was previously developed for rapid detection of genes from bacteria phagocytized by neutrophils. SBP may develop after bacteria enter into the systemic circulation following bacterial translocation. There...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2011
ISSN: 0270-9139
DOI: 10.1002/hep.24303